PVT1 interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma
Multiple myeloma is a heterogeneous hematological disease that originates from the bone marrow and is characterized by the monoclonal expansion of malignant plasma cells.Despite novel therapies, multiple myeloma remains clinically challenging.A common feature among Toppers patients with poor prognosis is the increased activity of the epigenetic sil